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🌿 Top Positive Cannabis Studies (2024–2025)

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1. 🧠 PTSD Symptom Relief

A long-term U.S. observational study found that cannabis users with PTSD were 2.6× more likely to no longer meet criteria for PTSD after 1 year.

2. 💨 Chronic Pain Reduction

A meta-analysis published in The Lancet Psychiatry concluded that THC and CBD combinations significantly reduce chronic pain, especially in conditions like arthritis, fibromyalgia, and neuropathic pain.

  • Result: Pain scores dropped by up to 30%

  • Patients also reported reduced opioid use

3. 🎗️ Cancer Symptom Management

A UK-wide registry study of cancer patients using cannabis-based medicinal products (CBMPs) reported:

  • Better sleep, less pain, and reduced nausea

  • Improved quality of life scores sustained at 6-month follow-up

  • Source: Project Twenty21 / Drug Science UK

4. 🧓 Improved Quality of Life in Older Adults

A 2025 Canadian study found that older adults (age 60+) with chronic pain or insomnia who used high-CBD cannabis:

  • Reported less anxiety, better sleep, and improved daily functioning

  • Reduced use of sleep aids, opioids, and antidepressants

5. ⚖️ Reduced Opioid Use & Overdose Risk

Studies from states with legalized cannabis show:

  • Up to 25% fewer opioid overdose deaths

  • Patients prescribed medical cannabis used fewer opioids and benzodiazepines

  • Source: JAMA Internal Medicine

6. 🧬 Neuroprotective & Anti-inflammatory Potential

Animal studies and early human trials show that CBD and low-dose THC may reduce neuroinflammation, relevant to:

  • Alzheimer’s, multiple sclerosis, Parkinson’s

  • Some evidence for slowing neurodegeneration and improving cognition

7. 🚼 Epilepsy (CBD – Epidiolex)

The FDA-approved drug Epidiolex (CBD isolate) significantly reduces seizures in children with Lennox-Gastaut and Dravet syndrome.

  • Seizure frequency cut by 39–50%

  • Well tolerated with minimal sedation compared to traditional anti-epileptics

🧪 Summary Table

Condition

Cannabis Benefit

Type of Study

PTSD

Reduced nightmares, better sleep

Longitudinal / Observational

Chronic pain

Less pain, lower opioid use

Meta-analysis / RCTs

Cancer

Better sleep, appetite, mood

Registry study

Older adults

Improved daily life, sleep, anxiety

Clinical follow-up study

Epilepsy

Dramatic seizure reduction (CBD)

FDA-approved RCTs

Alzheimer's

Reduced inflammation, possible memory aid

Early trials / Animal models


 
 
 

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